Green Tea

Anti-Cancer Mechanism of Green Tea Revealed

Food.Tea.GreenLactate dehydrogenase A (LDHA) is an enzyme that is elevated in several human cancers, including pancreatic cancer. Wai-Nang Lee, MD, from the Los Angeles Biomedical Research Institute (LA BioMed; California, USA), and colleagues observe that epigallocatechin gallate (EGCG), the active biologic constituent in green tea, changes the metabolism of pancreatic cancer cells by suppressing LDHA expression.

The researchers also found an enzyme inhibitor, oxamate, which is known to reduce LDHA activity, operated in the same manner: It also disrupted the pancreatic cancer cells metabolic system. The study authors submit that: “These results suggest that phytochemical [epigallocatechin gallate] and LDHA inhibitor oxamate confer their anti-cancer activities by disrupting the balance of flux throughout the cellular metabolic network.”

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Source: MedicineNet.

 


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Diet Rich in Plant Antioxidants Helps Blood Sugar

Food.Chocolate.DarkA substance found in a variety of plant-based foods may improve blood sugar in people at risk for heart disease and diabetes, according to a recent study.

Researchers found that a diet rich in plant antioxidants (called polyphenols) lowered blood sugar. The antioxidants are found in dark chocolate, green tea, coffee, and extra virgin olive oil, among other foods.

Lead researcher Lutgarda Bozzetto, MD, says the people in the study felt the diet was easy to stick with. Bozzetto is with the University of Naples Federico II in Italy and presented the study at the European Atherosclerosis Society 2014 Congress.

In this new study, 45 overweight or obese people followed one of four diets:

  • A diet low in omega-3 fatty acids and polyphenols
  • A diet rich in omega-3 fatty acids
  • A diet rich in polyphenols
  • A diet that included omega-3 fatty acids and polyphenols (in lower amounts than group 3)

Those on the omega-3 fatty acid-enriched diets lost more weight during the 8-week study. But blood sugar and insulin levels improved more with the polyphenol-enriched diet. The researchers also noticed improvements in the way the pancreas worked in people on the polyphenol-enriched diet.

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Source: MedicineNet.


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Green Tea Extract Boosts Your Brain Power, Especially the Working Memory

Food.Tea.GreenGreen tea is said to have many putative positive effects on health. Now, researchers at the University of Basel are reporting first evidence that green tea extract enhances the cognitive functions, in particular the working memory. The Swiss findings suggest promising clinical implications for the treatment of cognitive impairments in psychiatric disorders such as dementia. The academic journal Psychopharmacology has published their results.

In a new study, the researcher teams of Prof. Christoph Beglinger from the University Hospital of Basel and Prof. Stefan Borgwardt from the Psychiatric University Clinics found that green tea extract increases the brain’s effective connectivity, meaning the causal influence that one brain area exerts over another. This effect on connectivity also led to improvement in actual cognitive performance: Subjects tested significantly better for working memory tasks after the admission of green tea extract.

“Our findings suggest that green tea might increase the short-term synaptic plasticity of the brain,” says Borgwardt.

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Source: University of Basel. “Green tea extract boosts your brain power, especially the working memory, new research shows.” ScienceDaily. ScienceDaily, 7 April 2014.

Green Tea Supports Heart Health

Food.Tea.GreenGreen tea contains antioxidants of the polyphenol family of 30% to 40%. Previous studies suggest that these antioxidant compounds exert beneficial effects on parameters of cardiovascular health. Onakpoya, from the University of Oxford (United Kingdom), and colleagues who completed a meta-analysis of published randomized controlled trials, involving a total of subjects of 1,536, of green tea and its polyphenol constituents. The researchers found that green tea consumption associated with a lower average systolic blood pressure. In addition, green tea consumption correlated to lower total and LDL cholesterol levels.

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Source: WorldHealth.net