Is cancer an inevitable consequence of aging?

Although it is widely thought that cancer is an inevitable consequence of aging, the risk of developing several common cancers decreases with age.

Researchers have long been puzzled by the apparent decrease with age in the risk of developing certain adult cancers.

A possible solution to this puzzle was presented in a recent paper published in Biophysical Reviews and Letters by Professor James P. Brody of the Department of Biomedical Engineering at the University of California, Irvine.

“Most cancers have a characteristic age at which they occur. Testicular cancers mostly occur from age 25-40, bone sarcomas in the teens. Beyond the characteristic age, the incidence of these cancers decreases. Several common cancers appear to have a characteristic age greater than the typical lifespan. Observations of these cancers have led to the belief that the incidence of these cancer increases without limit.

One possible explanation is that many cancers originate early in life, possibly before birth. This is called the developmental origin of disease hypothesis. If true, this suggests that a test could be developed that would determine whether a person might develop a specific form of cancer decades before they actually develop it.

Ultimately this test would lead to earlier diagnosis and preventing many forms of cancer from ever developing to the life threatening stage.

Read the full story.

Source: Medical News Today

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